92 Results for "

Pinus radiata D. Don

" in MedChemExpress (MCE) Product Catalog:
Products (92)

92 Results for "Pinus radiata D. Don" in MCE Product Catalog:

22
Lycorine hydrochloride
Lycorine hydrochloride
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22 Publications Verification
Cat. No.: HY-N0289
CAS No.: 2188-68-3
Category:  

Alkaloids Lycoris radiata (L’Her.) Herb. Pyrrole Alkaloids Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Amaryllidaceae Cancer

Target:  

Autophagy Bacterial Virus Protease

Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (L’Her.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity . Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells (IC50 of 1.2 μM) .
14
6-Diazo-5-oxo-L-nor-Leucine
6-Diazo-5-oxo-L-nor-Leucine
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14 Cited Publications
Cat. No.: HY-108357
CAS No.: 157-03-9
Purity:  99.98%
Synonyms: L-6-Diazo-5-oxonorleucine; Don
Target:  

Glutaminase Bacterial Influenza Virus Antibiotic

Research Areas:  

Infection Cancer

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
9
JHU-083
JHU-083
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9 Cited Publications
Cat. No.: HY-122218
CAS No.: 1998725-11-3
Purity:  ≥98.0%
Target:  

Glutaminase

Research Areas:  

Neurological Disease

JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
1
Dehydroabietic acid
Dehydroabietic acid
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1 Cited Publications
Cat. No.: HY-N6869
CAS No.: 1740-19-8
Category:  

Infection other families Microorganisms Anti-aging Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Antibiotic PPAR Bacterial Fungal

Dehydroabietic acid is a diterpene resin acid that can be isolated from Pinus and Picea. Dehydroabietic acid has anti-bacterial, anti-fungal, anti-inflammatory, and anticancer activities. Dehydroabietic acid is a dual PPAR-α/γ agonist and PPAR-γ partial agonist, which can attenuate insulin resistance (IR) and hepatic steatosis induced by HFD-consumption in mice .
1
Wheat Germ Agglutinin (Fluorescein)
Wheat Germ Agglutinin (Fluorescein)
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1 Cited Publications
Cat. No.: HY-NP0147
Synonyms: WGA (Fluorescein)
Wheat Germ Agglutinin (WGA) Fluorescein is a classic fluorescent label that specifically binds to sugar residues such as N-acetylglucosamine, N-acetylneuraminic acid and sialic acid. Wheat Germ Agglutinin Fluorescein performs regionally differential fluorescent staining of the ocular surface epithelial glycocalyx to assess its integrity, and causes no damage to the eye at safe concentrations. Wheat Germ Agglutinin Fluorescein is also used for staining structures including red blood cells, cultured cells, bacteria and pine wood nematodes, and facilitates the isolation of wheat-associated plant-growth-promoting rhizobacterial strains. Wheat Germ Agglutinin Fluorescein can be applied to the detection of ocular glycocalyx integrity and the research of related diseases such as pine wilt disease .
Deoxynivalenol-3-β-D-glucoside
Deoxynivalenol-3-β-D-glucoside
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Cat. No.: HY-N11678
CAS No.: 131180-21-7
Synonyms: Don-3-β-D-glucoside; Deoxynivalenol 3-glucoside
Category:  

Natural Products Microorganisms

Target:  

Drug Metabolite

Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .
Pinosylvin
Pinosylvin
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Cat. No.: HY-N2387
CAS No.: 22139-77-1
Category:  

Infection Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial Apoptosis Autophagy

Pinosylvin is a?pre-infectious stilbenoid toxin?isolated from the heartwood of Pinus species, has anti-bacterial activities . Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells .
Pinobanksin 3-acetate
Pinobanksin 3-acetate
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Cat. No.: HY-N1854
CAS No.: 52117-69-8
Category:  

Flavanonols Flavonoids Animals Other Diseases Scrophulariaceae Eremophila alternifolia Plants Disease Research Fields

Target:  

Drug Derivative Apoptosis Wnt

Pinobanksin 3-acetate is a flavanone and flavonoid ester with antioxidant activity. Pinobanksin 3-acetate is naturally present in Sonoran propolis, honey, medicinal plants, and forestry coproducts of Pinus caribaea. Pinobanksin 3-acetate exerts anti-colorectal cancer activity by modulating proliferation, apoptosis, cell cycle, and Wnt signaling pathways. Pinobanksin 3-acetate can be used for the research of colon cancer .
Dihexadecyl hydrogen phosphate
Dihexadecyl hydrogen phosphate
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Cat. No.: HY-W099547
CAS No.: 2197-63-9
Dihexadecyl hydrogen phosphateIt is an organic compound belonging to phospholipids. It's often used as an emulsifier, which means it helps mix two substances together that don't usually mix well, such as oil and water. Dihexadecyl hydrogen phosphateIt has several applications in the food industry, especially in the production of processed foods where it improves texture and stability. Additionally, it has applications in the pharmaceutical industry where it can be used ain the generation of micelles, liposomes, and other types of artificial membranes.
(+)-Isolariciresinol
(+)-Isolariciresinol
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Cat. No.: HY-14579
CAS No.: 548-29-8
Purity:  97.28%
Synonyms: (+)-Cyclolariciresinol
Category:  

other families Lignans Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Drug Derivative

(+)-Isolariciresinol ((+)-Cyclolariciresinol) is a lignan that can be isolated from the roots of Bursera tonkinensis Guillaum and the needles of Pinus densiflora .
o-Vanillin
o-Vanillin
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Cat. No.: HY-Y1832
CAS No.: 148-53-8
Synonyms: 3-Methoxysalicylaldehyde
Target:  

Fungal

Research Areas:  

Infection Cancer

o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation .
Pinolenic acid
Pinolenic acid
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Cat. No.: HY-119546
CAS No.: 16833-54-8
Purity:  ≥98.0%
Synonyms: PNLA
Category:  

Pinaceae Ketones, Aldehydes, Acids Pinus koraiensis Siebold et Zuccarini Plants

Target:  

Free Fatty Acid Receptor

Pinolenic acid (PNLA) is a polyunsaturated fatty acid that can be isolated from Pinus orientalis and Pinus pinaster seed oil. Pinolenic acid has anti-inflammatory and lipid-lowering activities .
Safimestomig
Safimestomig
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Cat. No.: HY-P991023
CAS No.: 2911590-72-0
Synonyms: 6MW3211

Target:  

CD47 PD-1/PD-L1

Research Areas:  

Cancer

Safimestomig (6MW3211) is an CD47/PD-L1-targeting bispecific antibody. Safimestomig blocks CD47-mediated 'don't eat me' signaling and selectively binds to CD47 on tumor cells. Safimestomig blocks PD-L1-mediated immune checkpoint signaling. Safimestomig can be used for the research of cancer .
Pinus pinaster bark extract
Pinus pinaster bark extract
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Cat. No.: HY-N14039
CAS No.: 90082-75-0
Category:  

Natural Products Pinaceae Pinus pinaster. Plants

Target:  

Toll-like Receptor (TLR) Interleukin Related

Pinus pinaster bark extract is extracted from the bark of pine bark with antioxidant, anti-inflammatory and neuroprotective effects. Pinus pinaster bark extract increases toll-like receptor (TLR) activity, inducing production of IL-10 .
JHU395
JHU395
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Cat. No.: HY-128775
CAS No.: 2079938-92-2
Purity:  99.88%
Target:  

Drug Derivative

Research Areas:  

Cancer

JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
Acid Red sodium
Acid Red sodium
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Cat. No.: HY-D0854
CAS No.: 3244-88-0
Synonyms: Acid Violet 19; Acid fuchsin sodium
Acid Red is a class of synthetic dyes commonly used in the textile, paper and ink industries. They are in the category of acid dyes, which means they are water soluble and have acidic properties. Acid Red dye produces bright, vibrant colors that don't fade easily, but are not as durable as some other dyes. They can be used to dye a wide variety of fibers including wool, silk and nylon, as well as paper and leather.
trans-3,5-Dimethoxystilbene
trans-3,5-Dimethoxystilbene
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Cat. No.: HY-W278867
CAS No.: 21956-56-9
Synonyms: trans-Pinosylvin dimethyl ether
Category:  

Stilbenes Leguminosae Plants Disease Research Fields Inflammation/Immunology Astragalus membranaceus (Fisch.) Bunge

Target:  

Cholinesterase (ChE)

trans-3,5-Dimethoxystilbene (trans-Pinosylvin dimethyl ether) is a natural stilbenoid metabolite. trans-3,5-Dimethoxystilbene acts as an acetylcholinesterase inhibitor with a IC50 of 9 μM against Electrophorus electricus acetylcholinesterase. trans-3,5-Dimethoxystilbene binds to acetylcholinesterase and blocks acetylcholine hydrolysis, thereby increasing acetylcholine levels in the cholinergic synaptic cleft. trans-3,5-Dimethoxystilbene can be used in the research of neurodegenerative diseases such as Alzheimer's disease .
7-Oxodehydroabietic acid
7-Oxodehydroabietic acid
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Cat. No.: HY-133620
CAS No.: 18684-55-4
Purity:  99.67%
Target:  

Insecticide

Research Areas:  

Infection

7-Oxodehydroabietic acid is a diterpene resin acid isolated from the roots of the pine Pinus densiflora. 7-Oxodehydroabietic acid play a defensive role against herbivorous insects via insect endocrine-disrupting activity .
Dehydro-α-lapachone
Dehydro-α-lapachone
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Cat. No.: HY-N3706
CAS No.: 15297-92-4
Category:  

Catalpa ovata G. Don Plants Bignoniaceae

Target:  

Fungal

Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
Neoabietic acid (Standard)
Neoabietic acid (Standard)
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Cat. No.: HY-133592R
CAS No.: 471-77-2
Target:  

Reference Standards Bacterial

Research Areas:  

Infection

Neoabietic acid (Standard) is the analytical standard of Neoabietic acid. This product is intended for research and analytical applications. Neoabietic acid, an abietic-type acid, is a nature product that could be isolated from the oleoresin and rosin of Pinus palustris. Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity .
Assay Types